Please identify the computer to which you are trying to deploy a Puppy: Manufacturer, Version, Specs including in particular RAM and anything relating to your touchpad.
Also identify all operating systems you have available. Also let us know what Linux and versions works on your computer. That may provide a clue as to how to get your touchpad working.
Not every Puppy can boot from every computer. Startup Disk Creator was created for Ubuntu. Even a Puppy which is 'Ubuntu-binary-compatible' --such as BionicPup64-- is not a 'Ubuntu'. As wizard wrote, you'll get better results with Unetbootin. See this post about how to edit the grub.cfg Unetbootin writes. viewtopic.php?t=8149.
To communicate with your touchpad a Puppy must have both the necessary drivers and firmware. Not every Puppy's ISO will include those for your computer's hardware. But Puppys are modular builds. If firmware for your touchpad is missing you may be able to download an fdrv.sfs that has the necessary version and swap it for the fdrv.sfs included in the ISO. If a driver is missing you may be able to swap the kernel (vmlinuz) and drivers (zdrv.sfs).
Can someone please advice mcman56 how to determine which drivers and firmware his computer requires AFTER he identifies the computer per my request above.