Hello @dcung.
I suspect that you will be mildly pleased with either ISO boot solutions; namely SG2D or Ventoy. They allow running of the distros you choose and saving persistence (save-sessions) with little chance of disturbing the boot sequences that exist on your system drive, yet experiencing all the glory each distro you boot offers.
The 2 solutions have different provisions where I have found that on rare occasions, Ventoy might not boot all PUPs; yet SG2D will. But, Ventoy will boot almost every ISO file (including the SG2D ISO) while SG2D will boot all PUPs, DOGs, KLV, and Ubuntu based ISO files.
Thus, the primary benefit you will gain is that you no long have to install an ISO file which offers persistence; merely download the ISO file to /BOOTISOS folder on the USB stick and boot it without installing. In the case of PUPs/DOGs/KLV/Ubuntus/Mint/etc, I recommend you save your persistence on your system drive preferably on a Linux partition (I keep all of my save sessions in a folder on a Linux partition named /Sessions).
These are the ONLY elementary notes you need for use of either of the ISO file solution(s) you choose.
Trust me, you wont look back once you build your USB
Personally I have NOT installed ANY DISTRO on my system drive(s) in several years. ISO file booting and saving the session (persistence) is a Frugal use without the headaches of the past. I mention this frequently to help those who have not tried the solutions to be able to frame the advantage of the solutions.
Enjoy