I had to replace my old mouse with a new one otherwise I would have never noticed this problem.
As soon as you setup the new mouse parameters for acceleration and threshold you'll end up with a mismatch in /root/.xset.sh and /tmp/xerrs.log . The failing .xset.sh file reads:
'xset m /10 2 c off r rate 500 6 s 600 600 s blank s expose'
This problem doesn't exist in Quirky64-8.5 as well as EasyOS Buster 2.3.3 -> . The .xset.sh file reads:
'xset m 10/10 2 c off r rate 660 25 s 600 600 s blank s expose'
Adjusting the failing line doesn't help at all.