Problem: Left-handed mouse revert back by itself to right-handed after being set-up to left side after boot-up.
I'm using a dvd, burned with a 9.6.3 iso version, on a Seco UDOO SBC x-86 N3160 1.6 Ghz, 4 GB (raspi size) and a std usb mouse with 2 buttons and a wheel. The problem arose(?) at least 2 separate times I booted the distro. All I did, after boot-up, was set-up the desktop and downloaded 'aisleriot' (solitaire card game) and 'nim' (wow programming langage, the only one I could work on after python
).
When the ghost change happened, I brought the setup dialog box again, only to see that my initial configuration to left-hand was still there (checked box). What I did was reclic on it to uncheck and rechecked the box. My mouse came back left-handed ... but again, only for a period of time (may be between 20 and 60 minutes). The last time the ghost was active was when I left the computer open for supper, and when I came back, around one hour later, the ghost has changed my mouse setup again 
Any idea ?
BTW Thanks to dimkr: this distro is incredibly responsive and you chose the right essentials: automatic firewall (how come is it so rare ?) and better an icon on the tray to assure and reassure that it is working.
bf