PowerISO for Linux is a powerful image file processing tool. Lots of formats (iso, daa, nrg, isz, cue, bin, mdf, mds, vhd, vdi & many others).
Yesterday I needed to install the first two parts of the game On The Rain-Slick Precipice of Darkness (from the Penny Arcade series) under Wine. They turned out to be in mdf/mds format. AcetoneISO did not open or mount them. I decided to try PowerISO.
GUI version.
The program didn't work. Dug a little. After unpacking, you need to give permissions to ALL (and libraries) files in the program folder (select all>>right mouse button on file>>Permissions>>a + x). Then she works (run poweriso.sh).
And here is the console version of the program, without the GUI.